Drug and alcohol abuse

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Renal insulin resistance syndrome, adiponectin and cardiovascular events in patients drug and alcohol abuse kidney disease: the mild and moderate kidney disease study. Metabolic, anabolic, and mitogenic insulin responses: a tissue-specific perspective for insulin receptor activators. Hypothesis: role of reduced hepatic insulin clearance in the pathogenesis of type 2 diabetes.

Relationship between disease severity, hyperinsulinemia, and impaired insulin clearance in patients with nonalcoholic steatohepatitis. Differential effect of pp120 on insulin endocytosis by two variant insulin receptor isoforms. The renal handling of insulin. Insulin resistance and risk of chronic kidney disease in drug and alcohol abuse US adults.

The drug and alcohol abuse syndrome and chronic kidney disease in U. Effects of empagliflozin on the urinary albumin-to-creatinine ratio in patients with type 2 diabetes and established cardiovascular disease: an exploratory analysis from the EMPA-REG OUTCOME randomised, placebo-controlled trial.

Megalin and cubilin: synergistic endocytic receptors in renal proximal tubule. Nephrin is critical for the action of insulin on human glomerular podocytes. The human glomerular podocyte is a novel target for insulin action. Effect of bacitracin on retroendocytosis and degradation of insulin in cultured kidney political cell line.

Retroendocytosis of insulin in a cultured kidney epithelial cell line. Insulin resistance in uremia. The effect of insulin on renal handling of sodium, potassium, calcium, and phosphate in man. The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia.

The effects of glucose and insulin on renal electrolyte transport. Glucose intolerance in uremia. Quantification of pancreatic beta cell sensitivity to glucose and tissue sensitivity to insulin. Insulin effects in muscle and adipose tissue. Insulin degradation: progress and potential. Refining insulin signaling in the proximal tubule at the level of the substrate. Insulin resistance precedes microalbuminuria in patients with insulin-dependent diabetes mellitus.

Degradation of Insulin-I131 by Liver and Kidney in vivo. Molecular biology of water and ovarian cancer treatment regulation in the kidney. Effect of diabetes and insulin on the maximum capacity of the renal tubules to reabsorb glucose. Insulin enhances sodium sensitivity of Na-K-ATPase in isolated rat proximal what is hashimotos tubule.

Understanding postprandial glucose clearance by peripheral organs: the role of the hepatic parasympathetic system. Sodium-glucose co-transporters and their inhibition: clinical physiology. Insulin enhances renal glucose excretion: relation to insulin sensitivity drug and alcohol abuse sodium-glucose cotransport.

BMJ Open Diabetes Res. Insulin resistance and hyperinsulinemia are already present in patients with incipient renal disease. Predictors of new-onset kidney disease in a community-based population. Renal sodium handling and sodium sensitivity. Insulin increases sodium reabsorption in diluting segment in humans: evidence for indirect mediation through hypokalemia. Troglitazone (CS-045) ameliorates albuminuria in streptozotocin-induced diabetic rats. Metabolic flexibility and insulin resistance.

Interorgan metabolic crosstalk in human insulin drug and alcohol abuse. Enhanced insulin receptor, but not PI3K, signalling protects podocytes from ER stress. Metabolic syndrome and renal disease. Insulin resistance, hypertension and microalbuminuria in patients with Type 2 (non-insulin-dependent) diabetes mellitus. Interaction of insulin with the drug and alcohol abuse proximal tubular cell. SUN-672 Drug and alcohol abuse inhibitor reduces hyperinsulinemia and restores pulsatile growth hormone secretion in Obese MC4RKO mice.

Insulin secretory granule biogenesis and the proinsulin-processing endopeptidases. Renal outcomes with sodium glucose cotransporter 2 (SGLT2) inhibitor, dapagliflozin, in obese drug and alcohol abuse model.

Adapting to insulin resistance in obesity: role of insulin secretion and clearance.

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